Journal of Machine and Computing


Optimized Classification and Prediction with Hybrid Machine Learning Models



Journal of Machine and Computing

Received On : 17 May 2025

Revised On : 16 September 2025

Accepted On : 13 October 2025

Published On : 21 October 2025

Volume 06, Issue 01

Pages : 220-231


Abstract


In recent years, there has been an increase in thyroid disorders. Early thyroid illness identification is a crucial endeavor because of its significance in metabolism. Although there are numerous studies on the identification of whether thyroid illness leads to cancer or not, in order to properly address and handle this condition, a timely and accurate medical diagnosis is crucial. Thyroid cancer detection and diagnosis could be enhanced by algorithms that utilize machine learning, which have achieved considerable amounts of interest especially in the medical field. This paper describes how machine learning techniques are being used to diagnose thyroid cancer. K-Nearest Neighbor, Decision Tree, Random orest, Ada-Boost with decision tree classifier, Gradient Boosting Classifier, Stochastic Gradient Boosting classifier, Extended Gradient Boosting Classifier, Extended Gradient Boosting Classifier with hyper parameter tuning, Extra Tree Classifier, Light GBM Classifier, Voting Classifier are among the machine learning approaches that are used and evaluated to assess how well they diagnose thyroid Cancer. The study evaluates the methods precision, recall, F1-score, and Accuracy. From all the above machine learning models Random Forest, Ada Boost, Extended gradient boosting classifier, Extra Tree Classifier, Light Gradient Boosting Machine outperforms the other models.


Keywords


Thyroid Detection, Machine Learning, Label Encoder, Voting Classifier.


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CRediT Author Statement


The authors confirm contribution to the paper as follows:

Conceptualization: Kalpana K Harish and Kuppala Saritha; Methodology: Kalpana K Harish; Software: Kuppala Saritha; Data Curation: Kalpana K Harish; Writing- Original Draft Preparation: Kalpana K Harish and Kuppala Saritha; Visualization: Kalpana K Harish; Investigation: Kuppala Saritha; Supervision: Kalpana K Harish; Validation: Kuppala Saritha; Writing- Reviewing and Editing: Kalpana K Harish and Kuppala Saritha; All authors reviewed the results and approved the final version of the manuscript.


Acknowledgements


I sincerely thank Dr. Syed Siraj Ahmed for his valuable support and generous contribution of time in completing this paper.


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No funding was received to assist with the preparation of this manuscript.


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Cite this article


Kalpana K Harish and Kuppala Saritha, “Optimized Classification and Prediction with Hybrid Machine Learning Models”, Journal of Machine and Computing, vol.6, no.1, pp. 220-231, 2026, doi: 10.53759/7669/jmc202606016.


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© 2026 Kalpana K Harish and Kuppala Saritha. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.