The early stages of the condition are notoriously difficult to diagnose due to the fact that abnormal cells with dimensions less than very small are notoriously difficult to spot by imaging. If identification occurs at an earlier stage, then there is a chance that the probability of extending the lifespan of the individual may increase. Nevertheless, because of the enormous dimensionality of the database space, timely diagnosis is a challenging task. In this paper, nodule segmentation is proposed using Enhanced Local Information Weighted Intuitionistic Fuzzy C-Means (ELWI-FCM) clustering. After pre-processing, segmentation is performed by ELWI-FCM. To optimize the performance of FCM, the improved Golden Eagle Optimization (IGEO) algorithm is used. For classifying the nodules as normal or affected, the pre-trained DenseNet201 model is utilized. Experiments are conducted over the LIDC-IDRI dataset. Experimental results show that the proposed ELWI-FCM-IGEO attains better accuracy, precision, F1-score, sensitivity, and specificity compared to existing models.
Keywords
Enhanced Local Information Weighted Intuitionistic, Fuzzy C-Means Clustering, Golden Eagle Optimization, DenseNet201.
N. Nasrullah, J. Sang, M. S. Alam, and H. Xiang, “Automated detection and classification for early stage lung cancer on CT images using deep learning,” Pattern Recognition and Tracking XXX, p. 27, May 2019, doi: 10.1117/12.2520333.
J. Pedrosa et al., “LNDb challenge on automatic lung cancer patient management,” Medical Image Analysis, vol. 70, p. 102027, May 2021, doi: 10.1016/j.media.2021.102027.
K. Gunjan, N. Singh, F. Shaik, and S. Roy, “Detection of lung cancer in CT scans using grey wolf optimization algorithm and recurrent neural network,” Health and Technology, vol. 12, no. 6, pp. 1197–1210, Oct. 2022, doi: 10.1007/s12553-022-00700-8.
Z. Ali, A. Irtaza, and M. Maqsood, “An efficient U-Net framework for lung nodule detection using densely connected dilated convolutions,” The Journal of Supercomputing, vol. 78, no. 2, pp. 1602–1623, Jun. 2021, doi: 10.1007/s11227-021-03845-x.
T. L. Chaunzwa et al., “Deep learning classification of lung cancer histology using CT images,” Scientific Reports, vol. 11, no. 1, Mar. 2021, doi: 10.1038/s41598-021-84630-x.
Bhattacharjee, R. Murugan, and T. Goel, “A hybrid approach for lung cancer diagnosis using optimized random forest classification and K-means visualization algorithm,” Health and Technology, vol. 12, no. 4, pp. 787–800, Jun. 2022, doi: 10.1007/s12553-022-00679-2.
T. Meraj et al., “Lung nodules detection using semantic segmentation and classification with optimal features,” Neural Computing and Applications, vol. 33, no. 17, pp. 10737–10750, May 2020, doi: 10.1007/s00521-020-04870-2.
S. A. Agnes and J. Anitha, “Efficient multiscale fully convolutional UNet model for segmentation of 3D lung nodule from CT image,” Journal of Medical Imaging, vol. 9, no. 05, May 2022, doi: 10.1117/1.jmi.9.5.052402.
S. Kido et al., “Segmentation of Lung Nodules on CT Images Using a Nested Three-Dimensional Fully Connected Convolutional Network,” Frontiers in Artificial Intelligence, vol. 5, Feb. 2022, doi: 10.3389/frai.2022.782225.
S. B and S. Mahesh, “Hybrid optimized MRF based lung lobe segmentation and lung cancer classification using Shufflenet,” Multimedia Tools and Applications, vol. 83, no. 17, pp. 52335–52364, Nov. 2023, doi: 10.1007/s11042-023-17570-5.
C. de Margerie-Mellon and G. Chassagnon, “Artificial intelligence: A critical review of applications for lung nodule and lung cancer,” Diagnostic and Interventional Imaging, vol. 104, no. 1, pp. 11–17, Jan. 2023, doi: 10.1016/j.diii.2022.11.007.
M. Tsivgoulis, T. Papastergiou, and V. Megalooikonomou, “An improved SqueezeNet model for the diagnosis of lung cancer in CT scans,” Machine Learning with Applications, vol. 10, p. 100399, Dec. 2022, doi: 10.1016/j.mlwa.2022.100399.
S. Jain, S. Indora, and D. K. Atal, “Lung nodule segmentation using Salp Shuffled Shepherd Optimization Algorithm-based Generative Adversarial Network,” Computers in Biology and Medicine, vol. 137, p. 104811, Oct. 2021, doi: 10.1016/j.compbiomed.2021.104811.
M. Navaneethakrishnan, M. V. Anand, G. Vasavi, and V. V. Rani, “Deep Fuzzy SegNet-based lung nodule segmentation and optimized deep learning for lung cancer detection,” Pattern Analysis and Applications, vol. 26, no. 3, pp. 1143–1159, Feb. 2023, doi: 10.1007/s10044-023-01135-1.
Z. Ren, Y. Zhang, and S. Wang, “LCDAE: Data Augmented Ensemble Framework for Lung Cancer Classification,” Technology in Cancer Research & Treatment, vol. 21, Jan. 2022, doi: 10.1177/15330338221124372.
S. U. Atiya, N. V. K. Ramesh, and B. N. K. Reddy, “Classification of non-small cell lung cancers using deep convolutional neural networks,” Multimedia Tools and Applications, vol. 83, no. 5, pp. 13261–13290, Jul. 2023, doi: 10.1007/s11042-023-16119-w.
P. Nanglia, S. Kumar, A. N. Mahajan, P. Singh, and D. Rathee, “A hybrid algorithm for lung cancer classification using SVM and Neural Networks,” ICT Express, vol. 7, no. 3, pp. 335–341, Sep. 2021, doi: 10.1016/j.icte.2020.06.007.
Gopinath, P. Gowthaman, M. Venkatachalam, and M. Saroja, “Computer aided model for lung cancer classification using cat optimized convolutional neural networks,” Measurement: Sensors, vol. 30, p. 100932, Dec. 2023, doi: 10.1016/j.measen.2023.100932.
E. A. Siddiqui, V. Chaurasia, and M. Shandilya, “Detection and classification of lung cancer computed tomography images using a novel improved deep belief network with Gabor filters,” Chemometrics and Intelligent Laboratory Systems, vol. 235, p. 104763, Apr. 2023, doi: 10.1016/j.chemolab.2023.104763.
K. Ajai and A. Anitha, “Clustering based lung lobe segmentation and optimization-based lung cancer classification using CT images,” Biomedical Signal Processing and Control, vol. 78, p. 103986, Sep. 2022, doi: 10.1016/j.bspc.2022.103986.
Jacobs, E. M. van Rikxoort, K. Murphy, M. Prokop, C. M. Schaefer-Prokop, and B. van Ginneken, “Computer-aided detection of pulmonary nodules: a comparative study using the public LIDC/IDRI database,” European Radiology, vol. 26, no. 7, pp. 2139–2147, Oct. 2015, doi: 10.1007/s00330-015-4030-7.
Y. Zhu and S. Newsam, “DenseNet for dense flow,” 2017 IEEE International Conference on Image Processing (ICIP), Sep. 2017, doi: 10.1109/icip.2017.8296389.
CRediT Author Statement
The authors confirm contribution to the paper as follows:
Conceptualization: Sandhya L and Marimuthu Karuppiah;
Methodology: Sandhya L;
Data Curation: Sandhya L;
Writing- Original Draft Preparation: Sandhya L;
Visualization: Sandhya L;
Supervision: Marimuthu Karuppiah;
Validation: Marimuthu Karuppiah;
Writing- Reviewing and Editing: Sandhya L and Marimuthu Karuppiah; All authors reviewed the results and approved the final version of the manuscript.
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Marimuthu Karuppiah
Presidency School of Computer Science and Engineering, Presidency University, Bengaluru, Karnataka, India.
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Cite this article
Sandhya L and Marimuthu Karuppiah, “Enhanced Local Information Weighted Intuitionistic Fuzzy C-Means Clustering for Image Nodule Segmentation”, Journal of Machine and Computing, vol.5, no.4, pp. 2373-2385, October 2025, doi: 10.53759/7669/jmc202505184.