Journal of Computational Intelligence in Materials Science

Nano-Antibacterial Materials as an Alternative Antimicrobial Strategy

Journal of Computational Intelligence in Materials Science

Received On : 03 March 2023

Revised On : 31 March 2023

Accepted On : 22 April 2023

Published On : 28 April 2023

Volume 01, 2023

Pages : 045-055


Bacterial infections continue to be a leading cause of death and disability worldwide. Considering the increment in bacteria resistant to antibiotic and the prevalence of illnesses linked to biofilms, it is imperative that new strategies of killing bacteria be developed. As a result, recent years have seen a surge in interest in nanoparticle-based materials for use in antimicrobial chemotherapy. Bacterial infections have remained a significant source of death and morbidity, despite the availability of many powerful antibiotics and other antimicrobial measures. Because of rising worries about drug-resistant bacteria and diseases linked to biofilms, there is an urgent need to create new bactericidal techniques. As a result, the science of antimicrobial chemotherapeutic has focused heavily on recently developed nanoparticle-based materials. Nanoparticles are discussed in this article in terms of their antimicrobial properties, their method of action, their influence on drug-resistant microorganisms, and the hazards associated with their usage. Nanoparticles' special characteristics and their mode of action as antimicrobial properties are examined in depth, as are the factors that contribute to their performance in a clinical environment.


Nano-Antibacterial Materials, Nanoparticles, Organic Nanoparticles, Inorganic Nanoparticles.

  1. C. J. Diskin, “Heparin, biofilm, and catheter-related sepsis,” Diagnostic Microbiology and Infectious Disease, vol. 61, no. 1, p. 80, 2008.
  2. L. Guo, X. Yin, and Q. Liu, “Fecal microbiota transplantation reduces mouse mortality from listeria monocytogenes infection,” Microbial Pathogenesis, vol. 178, p. 106036, 2023.
  3. “Degradation of carbon-supported platinum-group-metal electrocatalysts in alkaline media studied by in situ Fourier transform infrared spectroscopy and identical-location transmission electron microscopy.”
  4. A. J. Banister, J. A. Durrant, I. B. Gorrell, and R. S. Roberts, “Structural deductions using (i) symmetric–antisymmetric stretching-frequency correlations for sulphur–oxygen and sulphur–nitrogen groups and (II) stretching-wavelength–bond-distance correlations for sulphur–oxygen and sulphur–nitrogen bonds,” J. Chem. Soc., Faraday Trans. 2, vol. 81, no. 12, pp. 1771–1782, 1985.
  5. “Detection of reactive oxygen species,” Reactive Oxygen Species in Biology and Human Health, pp. 41–48, 2017.
  6. D. Bell and F. Deng, “Superparamagnetic Iron Oxide,”, 2018.
  7. J. A. Ibemesi and D. J. Meier, “Synthesis of block copolymers of methyl siloxane, phenyl siloxane, vinyl siloxane, etc,” 1979.
  8. C. E. Carraher, M. R. Roner, R. E. Lambert, L. Arroyo, and L. C. Miller, “Synthesis of organotin polyamine ethers containing thiamine (vitamin B1) and preliminary ability to inhibit select cancer cell lines,” Journal of Inorganic and Organometallic Polymers and Materials, vol. 25, no. 6, pp. 1414–1424, 2015.
  9. Y. G. Wu, H. Tong, S. Y. Qiu, and X. Wang, “Preparation and bactericidal properties of nano-SIO2 grafted with macromolecular quaternary ammonium salts derivative of alkylated polyethylenimines,” High-Performance Ceramics V, pp. 1519–1522, 2008.
  10. H. J. Yoon and S. W. Suh, “Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from haemophilus influenzae in complex with UDP-N-acetylglucosamine,” 2008.


Author(s) thanks to Sri Eshwar College of Engineering for research lab and equipment support.


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Cite this article

Anandakumar H, “Nano-Antibacterial Materials as an Alternative Antimicrobial Strategy”, Journal of Computational Intelligence in Materials Science, vol.1, pp. 045-055, 2023. doi: 10.53759/832X/JCIMS202301005.


© 2023 Anandakumar H. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.