MediSCAPE, a high-speed 3D microscope designed by Columbia Engineers, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.

A Columbia Engineering team has developed a technology that could replace conventional biopsies and histology with real-time imaging within the living body. Described in a new paper published today (March 28, 2022) in Nature Biomedical Engineering, MediSCAPE is a high-speed 3D microscope capable of capturing images of tissue structures that could guide surgeons to navigate tumors and their boundaries without needing to remove tissues and wait for pathology results. [1]

Figure 1. New High-Speed 3D Microscope Could Make Biopsies a Thing of the Past

Figure 1 shows for many medical procedures, particularly cancer surgery and screening, it is common for doctors to take a biopsy, cutting out small pieces of tissue to be able to take a closer look at them with a microscope. "The way that biopsy samples are processed hasn't changed in 100 years, they are cut out, fixed, embedded, sliced, stained with dyes, positioned on a glass slide, and viewed by a pathologist using a simple microscope. This is why it can take days to hear news back about your diagnosis after a biopsy," says Elizabeth Hillman, professor of biomedical engineering and radiology at Columbia University and senior author of the study. [2]

One other main advantage of the method is that chopping tissue out, simply to determine what it's, is a tough choice for docs, particularly for treasured tissues such because the mind, spinal twine, nerves, the attention, and areas of the face. Because of this docs can miss vital areas of illness. “As a result of we will picture the residing tissue, with out chopping it out, we hope that MediSCAPE will make these choices a factor of the previous,” says Hillman. [3] Eager to take this technology to the next level with a larger clinical trial, the team is currently working on commercialization and FDA approval. Hillman adds, “We are just so amazed to see what MediSCAPE reveals every time we use it on a new tissue, and especially that we barely ever even needed to add dyes or stains to see structures that pathologists can recognize.” [4]

References:

1. https://scitechdaily.com/new-high-speed-3d-microscope-could-make-biopsies-a-thing-of-the-past/
2. https://www.sciencedaily.com/releases/2022/03/220328112123.htm
3. https://lightaholictech.blogspot.com/2022/03/new-high-speed-3d-microscope-could-make.html
4. https://vervetimes.com/high-speed-3d-microscope-can-see-real-time-cellular-detail-in-living-tissues-to-guide-surgery-speed-up-tissue-analyses-and-improve-treatments-sciencedaily/

Cite this article:

Thanusri swetha J (2022), New High-Speed 3D Microscope Could Make Biopsies a Thing of the Past, Anatechmaz, pp. 225